At Scan4Health Diagnostics, the Bence-Jones Protein (Urine) Test is performed using advanced laboratory techniques to detect specific light chains (kappa or lambda) that may indicate plasma cell disorders, such as multiple myeloma or related conditions. This test plays a crucial role when patients present with symptoms such as persistent bone pain, fatigue, recurrent infections, or unexplained anemia. Our clinical pathology team ensures accurate evaluation, timely reporting, and a patient-friendly experience, helping your doctor identify abnormal protein levels early and guide appropriate next steps in diagnosis and treatment.

• Your doctor may request either a random urine sample or a 24-hour urine collection. Follow the specific instructions given.
• Drink adequate water unless instructed otherwise. Proper hydration helps in collecting a clear sample.
• Inform the team if you are taking medications such as NSAIDs, diuretics, or high-dose vitamin C, as they may influence test interpretation.
• Avoid strenuous exercise for 24 hours before the test, as it may cause temporary protein loss in urine.
• Ensure the urine container provided by the lab is used strictly, especially for 24-hour collection.
• Bring any previous kidney function tests, serum protein tests, or myeloma reports for comparison.
• Carry a valid ID and your doctor's requisition for registration.

The Bence-Jones Protein (BJP) Test is a urine test used to detect free light chains, small protein fragments produced by abnormal plasma cells. Under normal conditions, these proteins are present in tiny amounts or not at all. However, in disorders such as multiple myeloma, light-chain myeloma, Waldenström’s macroglobulinemia, and amyloidosis, these proteins may appear in the urine at elevated levels.

The test is essential for:

• Screening for plasma cell disorders
• Confirming suspected multiple myeloma
• Evaluating kidney involvement caused by excess light chains
• Monitoring patients already diagnosed with myeloma
• Supporting differential diagnosis for unexplained proteinuria

The Bence Jones proteins pass easily through the kidneys due to their low molecular weight. When present in high levels, they can accumulate and cause kidney damage—making early detection critical.

Samples are analyzed using techniques such as protein electrophoresis, immunofixation, or light chain quantification, depending on the clinical requirement.

At Scan4Health Diagnostics, every sample undergoes thorough examination under expert supervision to deliver reliable results that help guide timely treatment decisions.