Gain clarity on autoimmune liver health with Scan4Health’s Anti-Mitochondrial Antibody (AMA) Test—a critical diagnostic tool for identifying primary biliary cholangitis (PBC), a chronic autoimmune liver disorder. AMA, especially the M2 subtype, is a specific marker that helps distinguish PBC from other liver and biliary diseases. With rapid, accurate results and detailed consultation, Scan4Health supports a complete path from diagnosis to ongoing care.

• Routine Preparation: No fasting is typically required. Continue your usual diet and activities unless directed otherwise.
• Medication Guidance: Share all medicines and supplements, especially immunomodulators and autoimmune treatments.
• Symptom/History: Mention symptoms of chronic liver disease, such as fatigue, jaundice, itching, right upper abdominal pain, dry mouth/eyes, unexplained weight loss, or swelling.
• Family/Risk Factors: Note any family history of autoimmune disorders or cholestatic liver conditions.
• Procedure Comfort: Wear a shirt with easy access for a simple blood draw.

The AMA test detects autoantibodies directed against mitochondria, the cellular structures necessary for energy production. The presence of AMA, and particularly the M2 subtype, is considered a serological hallmark of PBC, one of the most specific indicators for this autoimmune liver disease. PBC most commonly affects women between the ages of 35 and 60, causing progressive scarring of small bile ducts, liver inflammation, and long-term liver injury. AMA is measured through advanced immunoassays on a blood sample. Strong AMA positivity, alongside elevated liver enzymes (especially alkaline phosphatase) and compatible symptoms, helps clinicians make an early diagnosis of PBC and distinguish it from other causes of cholestatic or chronic liver disease. While up to 90–95% of PBC patients have significant AMA titers, diagnosis also relies on clinical findings and, when AMA is negative, may involve further autoantibody panels and liver biopsy. AMA may be rarely present in other autoimmune or infectious liver conditions, so results are interpreted in the context of the complete clinical picture.

Rely on Scan4Health for precise autoimmune liver disorder screening and care, comprehensive support. Book your Anti-Mitochondrial Antibody Test today for clarity and a confident plan for your liver health.