Take a foundational step in understanding your hepatitis B status and exposure history with Scan4Health’s Anti Hepatitis B Core Total (Anti-HBc Total) Test. This blood test checks for two types of antibodies against the core protein of the hepatitis B virus, providing important information about a current or past infection, even if other tests do not show it. With Scan4Health’s modern testing and expert advice, you get clear results to help you make good choices about your liver health and future care.

• Routine Preparation: No fasting is needed unless specified for other simultaneous tests.
• Medication Guidance: Inform your physician of all medications, especially antivirals, immunosuppressants, or recent vaccinations.
• Symptom/Health History: Share a comprehensive history, including previous hepatitis infection, chronic liver disease, unexplained jaundice, intravenous drug use, or high-risk exposures.
• Risk Factors: Health workers, travelers to endemic regions, individuals with a history of blood transfusions, or those at risk for chronic liver disease should inform the care team if this affects the need for HBV screening.
• Procedure Comfort: Dress for easy blood sample collection from your arm.

This important blood test detects antibodies your body forms against the hepatitis B core antigen (HBc). Unlike antibodies generated from the hepatitis B vaccine (which targets the surface antigen), HBc antibodies are only present after actual infection. The “total” assay measures both IgM (early response) and IgG (long-term response), providing a comprehensive picture of HBV exposure and the immune response, regardless of whether the infection is acute, chronic, or resolved.

Doctors order the Anti-HBc Total Test to:

• Help diagnose new (acute) and long-standing (chronic) hepatitis B infections.
• Confirm past exposure in those with known liver disease or unexplained hepatitis.
• Serve as a screening tool for blood and organ donors.
• Clarify hepatitis B status when surface antigen and antibody results are ambiguous.
• Monitor progression or resolution in HBV patients under treatment.

A positive result indicates past or current HBV infection. This marker persists for life—even after infection is resolved—unlike IgM, which fades after the acute phase. The test cannot differentiate between current and past infection, but, in combination with other hepatitis B markers (surface antigen, surface antibody, and e-antigen/antibody), it helps your physician stage the disease and guide therapy.

Choose Scan4Health for all-inclusive hepatitis diagnostic solutions and expert support, ensuring peace of mind and optimal liver health at every stage. Book your Anti Hepatitis B Core Total Test today for confident answers.