Discover peace of mind with Scan4Health’s 24-Hour Urinary Cortisol/Creatinine Ratio test—a vital diagnostic tool used to detect imbalances in your body’s stress and steroid hormones. This test is important for detecting adrenal gland problems, such as Cushing’s syndrome or Addison’s disease. It helps doctors find the right diagnosis and plan the best treatment for your long-term health. Our simple process, caring staff, and up-to-date lab ensure you get accurate results and feel supported every step of the way.

• Medication Guidance: Let your doctor know about every medication and supplement you use, including steroids, birth control pills, antidepressants, and water pills. Only stop taking a medicine if your doctor tells you to.
• Diet and Activities: Maintain normal food and fluid intake throughout the collection period unless advised otherwise. Avoid excessive physical or emotional stress, as these factors can temporarily alter cortisol levels.
• Collection Kit: Use only the provided sterile container and collect all urine for 24 hours. Do not add or remove anything from the collection bottle.
• Timing: Begin in the morning by discarding your first urination, then collect every subsequent urine—including the first urination the next morning—for precisely 24 hours.
• Hygiene: Ensure clean collection practices to prevent contamination. For infants or children, a collection bag may be required; ask your physician for guidance.
• Refrigeration: Keep the collection container refrigerated or on ice throughout the 24 hours.
• Prompt Submission: Return your full sample to the laboratory immediately after the last collection for prompt analysis.

This advanced non-invasive test analyzes two key substances in your urine—cortisol, a primary stress hormone made by your adrenal glands, and creatinine, a waste product that validates complete collection. By comparing the amounts of cortisol and creatinine collected over 24 hours, doctors obtain a standardized measure that reflects accurate hormonal output, filtering out fluctuations caused by urine dilution or hydration. This ratio is mainly used to determine whether your body is producing too much or too little cortisol. A high ratio might be a sign of Cushing’s syndrome. People with this condition may gain weight, have high blood pressure, weak muscles, and experience mood changes. Conversely, a low ratio could indicate Addison’s disease, a disorder in which the adrenal glands do not function properly. This can lead to tiredness, weight loss, and an increased risk of illness or stress. Doctors suggest this test if you have ongoing symptoms that might be linked to adrenal gland problems, unclear blood cortisol results, or possible pituitary issues. When you do the test, collect all your urine in the container provided. Be sure to keep track of the times and avoid missing any collections. Laboratory analysis quantifies both cortisol and creatinine, and experienced clinicians review results to place your levels in context—considering your age, symptoms, and other health markers. Rapid and reliable reporting allows your doctor to make informed treatment plans or order further assessments if needed.

Choose Scan4Health for advanced testing, compassionate care, and timely answers. Get clarity and actionable insight with the 24-Hour Urinary Cortisol/Creatinine Ratio test—your pathway to better adrenal and overall health.